KactusBio Inc.

Biotinylated Human HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer Protein (MHC-HM410B)

Product Code:
 
KAC-MHC-HM410B
Product Group:
 
MHC Monomers
Supplier:
 
KactusBio Inc.
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
Shipped at ambient temperature.
Storage:
 
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3 months after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Biotinylated Human HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%
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The purity of Biotinylated Human HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer is greater than 95% as determined by SEC-HPLC.
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Biotinylated Human HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%
The purity of Biotinylated Human HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer is greater than 95% as determined by SEC-HPLC.

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CodeSizePrice
KAC-MHC-HM410B-100UG100UG£327.00
Quantity:
KAC-MHC-HM410B-500UG500UG£1,073.00
Quantity:
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Background:
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of malignant tumors that highly express LMP2.
Biotinylated:
yes
Description:
Recombinant Biotinylated Human LMP2(HLA-A*11:01) Protein is expressed from HEK293 with with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*11:01),Ile21-Met119(B2M) and SSCSSCPLTK peptide.
Endotoxin:
Less than 1EU per ug by the LAL method.
Exact Sequence:
Gly25-Thr305(HLA-A*11:01),Ile21-Met119(B2M)and SSCSSCPLTK peptide
Expression System:
HEK293
Form:
Lyophilized
Formulation:
Lyophilized from 0.22um filtered solution in 20mM PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Gene/Protein ID:
AAV53343.1(HLA-A*11:01)&P61769(B2M)&SSCSSCPLTK
Molecular Weight:
The protein has a predicted MW of 50.4 kDa. Due to glycosylation, the protein migrates to 51-60 kDa based on Bis-Tris PAGE result.
Purity:
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Reconstitution:
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Synonyms:
MHC; RMF; LMP2; LMP-2; Macropain chain 7; Proteasome chain 7; PSMB9; RING12
Tag:
C-His-Avi
Target:
HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer

Documents