KactusBio Inc.

Human HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer Protein (MHC-HM420T)

Product Code:
 
KAC-MHC-HM420T
Product Group:
 
MHC Tetramers
Supplier:
 
KactusBio Inc.
Host Type:
 
HEK 293 cells
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
Shipped at ambient temperature.
Storage:
 
-20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
1 / 3
Immobilized HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) TCR at 1ug/ml (100ul/well) on the plate. Dose response curve for Human HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer, His Tag with the EC50 of 51.5ng/ml determined by ELISA
2 / 3
Human HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer on Bis-Tris PAGE under Non reducing (N) condition. The purity is greater than 95%
3 / 3
The purity of Human HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer is greater than 95% as determined by SEC-HPLC.
❮❯

Immobilized HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) TCR at 1ug/ml (100ul/well) on the plate. Dose response curve for Human HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer, His Tag with the EC50 of 51.5ng/ml determined by ELISA
Human HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer on Bis-Tris PAGE under Non reducing (N) condition. The purity is greater than 95%
The purity of Human HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer is greater than 95% as determined by SEC-HPLC.

No additional charges, what you see is what you pay! *

CodeSizePrice
KAC-MHC-HM420T-100UG100UG£676.00
Quantity:
KAC-MHC-HM420T-500UG500UG£2,463.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges to UK mainland customers, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Background:
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Biotinylated:
no
Description:
Recombinant Human KRAS G12D(HLA-A*11:01) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus, tetramer is assembled by biotinylated monomer and streptavidin. It contains Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and VVVGADGVGK peptide.
Endotoxin:
Less than 1EU per ug by the LAL method.
Exact Sequence:
Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and VVVGADGVGK peptide
Expression System:
HEK293
Form:
Lyophilized
Formulation:
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Gene/Protein ID:
AAV53343.1(HLA-A*11:01)&P61769(B2M)&VVVGADGVGK
Molecular Weight:
The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Bis-Tris PAGE result.
Purity:
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Reconstitution:
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Synonyms:
MHC; KRAS; K-Ras 2; KRAS2; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KRAS1; KRAS2; NS; NS3; RASK2; GTPase Kras; KI-RAS; RALD
Tag:
C-His-Avi
Target:
HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer

Documents