Applied Biological Materials (abm)

Human Primary Cardiomyocytes

Product Code:
 
ABM-T4037
Product Group:
 
Primary Cells
Cell System:
 
Cardiovascular Cell System
Cell Type:
 
Cardiac Myocytes
Species:
 
Human
Regulatory Status:
 
RUO
 

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ABM-T40375x10? cells / 1.0 mlEnquire
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This product comes from: Canada.
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Further Information

Description:
Human Primary Cardiomyocytes are isolated from human heart ventricles. Their specialized high-oxygen-content with a large number of mitochondria contributes to the major role of cardiac muscles in the heart?s rhythmic pumping. Cardiomyocytes are regulated by a complex network of signals. Cardiomyocytes hypertrophy and apoptosis have been associated with the loss of contractile function during heart failure. They are ideal models for study of cytokines and cellular signaling mechanisms that lead to myocyte death, as well as for research on mechanical strain and cell-cell interaction.
Donor History:
Normal tissue
Growth Conditions:
PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) are recommended for optimal cell culture. PriGrow X Series Medium (TM4037) + 1% Penicillin/Streptomycin Solution (G255), 37.0°C, 5% CO2.Cells can be expanded for up to 15 population doublings. Cells are sensitive to trypsin; Gentle Dissociation Solution (TM080) is recommended for subculture procedures. 
Growth Properties:
Adherent, multipolar
Markers:
Sarcomeric alpha-actinin, slow muscle myosin
Seeding Density (/cm^2):
10,000 - 15,000
Tissue:
Heart