immunAware

HLA-B*15:01 | easYmer kit

Product Code:
 
IMM-1058-01
Product Group:
 
MHC Tetramers
Supplier:
 
immunAware
Regulatory Status:
 
RUO
Shipping:
 
Dry Ice
Storage:
 
-20 °C
 

No additional charges, what you see is what you pay! *

CodeSizePrice
IMM-1058-01-05050 Tests£956.00
Quantity:
IMM-1058-01-100100 Tests£1,220.00
Quantity:
IMM-1058-01-150150 Tests£1,749.00
Quantity:
IMM-1058-01-200200 Tests£2,278.00
Quantity:
IMM-1058-01-250250 Tests£2,807.00
Quantity:
IMM-1058-01-300300 Tests£3,336.00
Quantity:
IMM-1058-01-500500 Tests£3,865.00
Quantity:
Prices exclude any Taxes / VAT
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* Rare exceptions are clearly labelled (only 0.14% of items!).
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This product comes from: Denmark.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
  • Further Information
  • References
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Further Information

Description:
HLA-Class I easYmer® is a highly active formulation of peptide-receptive HLA class I (HLA-I) molecules (no artificial Cys-bonds linking heavy chain and b2m). Add Peptides of interest to generate specific peptide-HLA class I monomers. The loading efficacy can be validated in a FACS-based bead assay. The monomers can easily be tetramerised with fluorophore-conjugated streptavidin and used to stain cognate T cells for analysis in a flow cytometric assay. The easYmer® technology seamlessly enables: Large-scale production of pMHC monomers with a single epitope for screening a large number of samples, parallel production and screening of pMHC monomers with many different peptide epitope candidates and screening and validation of peptide-HLA-I binding. easYmers® are available in aliquots of 50 Tests (corresponding to 20 ug of pMHC)

References

  • Augusto, DG; et.al.; A common allele of HLA mediates asymptomatic SARS-CoV-2 infection; medRxiv : the preprint server for health sciences; 2022; ():PubMed ID:34031661; DOI: 10.1101/2021.05.13.21257065; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142661
  • Minervina, AA; et.al.; SARS-CoV-2 antigen exposure history shapes phenotypes and specificity of memory CD8+ T cells; Nature immunology; 2022; 23(5):781-790PubMed ID:35383307; DOI: 10.1038/s41590-022-01184-4; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106845
  • Landau, N; et.al.; A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection.; Faculty Opinions ? Post-Publication Peer Review of the Biomedical Literature; 2023; ():PubMed ID:; DOI: 10.3410/f.742721563.793599881; https://www.nature.com/articles/s41586-023-06331-x
  • Ryu, H; et.al.; Merkel cell polyomavirus-specific and CD39+CLA+ CD8 T?cells as blood-based predictive biomarkers for PD-1 blockade in Merkel cell carcinoma; Cell reports. Medicine; 2024; 5(2):101390PubMed ID:38340724; DOI: 10.1016/j.xcrm.2023.101390; https://www.cell.com/cell-reports-medicine/pdf/S2666-3791(23)00619-5.pdf