Mikrogen Diagnostik recomLine HTLV-1 & HTLV-2 IgG Lateral Strip Test Kit

The human T-lymphotropic virus (HTLV) is a retrovirus, which can cause rare but severe diseases like adult T-cell leukemia (ATL) or HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) in humans. Several HTLV types are known of which HTLV-1 and HTLV-2 are the most prevalent ones. It is possible to discriminate between HTLV-1 and HTLV-2 with molecular and serological diagnostic methods. HTLV prevalence greatly varies by region and is highest in endemic areas like Japan, South America, the Caribbean and certain parts of Africa. In Europe a relevant prevalence can be found in countries with historical ties to these regions, but also for example in Romania. The total number of HTLV-infected persons can only be roughly estimated, the numbers are incomplete and range up to a total of more than 20 million cases worldwide. The virus depends on a direct cell-cell contact to establish an infection. Due to this, blood plasma is not considered as an infective agent. Vertical mother to child transmission, especially during breastfeeding, is one of the most common routes of infection. Moreover, transmission through unprotected sexual contact, drug use and contaminated blood products or transplants is also relevant. Since there is no curative therapy for HTLV, diagnostics is key to contain the virus. Only by the means of fast and reliable diagnostics the risk of vertical transmission through infected mothers can be reduced and safety of blood products and transplants can be guaranteed. Usually HTLV diagnostic is performed in two steps: A positive or ambiguous result of a serological screening test is followed by a confirmatory assay, such as a line immunoassay. The recomLine HTLV-1 & HTLV-2 IgG is a qualitative test for the detection of IgG antibodies against HTLV-1 as well as HTLV-2 in human serum or plasma. The test is able to discriminate between virus type 1 and type 2 on one strip, therefore it is ideal for a simple and safe confirmation of screening results.Research Use Only. For Sale In the United States Only. To purchase outside of the US, please contact Mikrogen.

Human T-lymphotropic virus type 1 (HTLV-1) and type 2 (HTLV-2) IgG