Elabscience

Caspase 1 Activity Detection Substrate for Flow Cytometry

Product Code:
 
E-CK-A481
Product Group:
 
Substrates
Supplier:
 
Elabscience
Regulatory Status:
 
RUO
Shipping:
 
Ice bag
Storage:
 
This product can be stored at -20°C for 1 year in the dark.
 

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CodeSizePrice
E-CK-A481-20Tests20Tests£192.00
Quantity:
E-CK-A481-100Tests100Tests£359.00
Quantity:
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This product comes from: China.
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Further Information

Assay Time:
30 min
Detection Instrument:
Flow Cytometer;Fluorescence microscope
Detection Type:
Fluorometric method;Flow cytometry
Test Principle:
The Caspase 1 Activity Detection Substrate for Flow Cytometry are a novel fluorogenic dye that couple the caspase 1 recognition sequence (YVAD) to a high affinity DNA dye, which have cell membrane permeability and can penetrate the plasma membrane into the cytoplasm. The substrate itself has no fluorescence and has a charge exclusion effect with DNA. During cell apoptosis, caspase-1 cleaves the substrate and releases high affinity DNA dyes, which bind to DNA to produce strong fluorescence, thereby detecting caspase-1 activity and visualizing the morphological changes of the cell nucleus during apoptosis.
Tested Sample Types:
Cell samples
Type:
Apoptosis/Caspase

Documents