TargetMol

JAK2-IN-11

Product Code:
 
TAR-T201601
Product Group:
 
Substrates
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
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TAR-T201601-10mg10 mgEnquire
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TAR-T201601-50mg50 mgEnquire
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This product comes from: Austria.
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Further Information

Bioactivity:
JAK2-IN-11 (Example 6) is a JAK2 kinase inhibitor with potent antitumor activity, exhibiting an IC50 of ≤10 nM against JH2 BIND WT/V617F. This compound effectively suppresses tumor growth.
CAS Number:
3057053-17-2
Formula:
C31H31F3N8O4
Molwt:
639.64
Pathway:
Angiogenesis|JAK/STAT signaling|Chromatin/Epigenetic|Tyrosine Kinase/Adaptors|Stem Cells
SMILES:
O=C1N(C=2C(N1C([2H])([2H])[2H])=CN=C(NC3=NC4=C(C(C(=O)N5CCC(C#N)CC5)=C3)C=CC=C4C(F)(F)F)C2)[C@H]6C[C@H](NC(OC)=O)CC6
Target:
JAK

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