TargetMol

DOTA-cyclo(RGDfK)

Product Code:
 
TAR-T203015
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T203015-1mg1 mgEnquire
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This product comes from: Austria.
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Further Information

Bioactivity:
DOTA-cyclo(RGDfK) is a and DOTA-like chelator peptide consisting of a dimer of the peptide cross-linker DOTA and the cyclic peptide RGDFK, which preferentially targets the αvβ3 integrin receptor expressed on tumor cell membranes, allowing for the preparation of radionuclide coupled compounds (RDCs) and their use in cancer diagnostics and therapy.
CAS Number:
909024-55-1
Formula:
C43H67N13O14
Molwt:
990.07
Pathway:
Cytoskeletal Signaling
SMILES:
C([C@@H]1C(=O)N[C@@H](CCCCNC(CN2CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC2)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N1)C3=CC=CC=C3
Target:
Integrin

Documents

References

Zeller Meidell K, et al. RGDfK-functionalized gold nanorods bind only to activated platelets. J Biomed Mater Res A. 2017 Jan;105(1):209-217.