TargetMol

Extracellular Death Factor TFA

Product Code:
 
TAR-T36523L
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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CodeSizePrice
TAR-T36523L-1mg1 mgEnquire
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TAR-T36523L-10mg10 mgEnquire
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TAR-T36523L-25mg25 mgEnquire
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TAR-T36523L-5mg5 mgEnquire
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This product comes from: Austria.
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Further Information

Bioactivity:
Extracellular Death Factor TFA (EDF TFA) is a linear pentapeptide that is produced and released by communicating cells and activates cell death pathways in cellular subpopulations when sufficient concentrations are reached.EDF TFA is sensitive to extreme pH, high temperatures, and other stressful conditions. At a concentration of 2.5 ng/ml, EDF has been shown to promote mazeEF (toxin-antitoxin system within bacteria) mediated cell death, promote the endonuclease activity of MazF toxin, lead to degradation of bacterial mRNA, and significantly reduce population size in E. coli cultures.
Pathway:
Microbiology/Virology
Purity:
0.9877
Target:
Antibacterial

Documents

References

Yan Z, et al. The extracellular death factor (EDF) protects Escherichia coli by scavenging hydroxyl radicals induced by bactericidal antibiotics. Springerplus. 2015 Apr 16;4:182.