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Further Information
Bioactivity:
TAPI1 acetate is a salt form of TAPI1. TAPI1 (TNF-α processing inhibitor-1) is a TACE (ADAM17) inhibitor that inhibits shedding of TNF-α, TNFRI (p60), and TNFRII (p80), IL-6 other cytokine receptors; TAPI-1 is also a metalloproteinase MMP inhibitor that promotes cisplatin-induced ESCC cell apoptosis by inhibiting the NF-κB signaling pathway to promote cisplatin-induced apoptosis in ESCC cells.