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Further Information
Bioactivity:
SIRT-IN-3, a potent inhibitor of SIRT1 with an IC50 value of 17 uM, exhibits approximate 4-fold and 14-fold greater selectivity for SIRT1 over SIRT2 and SIRT3, with respective IC50 values of 74 uM for SIRT2 and 235 uM for SIRT3 [1].
