TargetMol

GDC-2394 sodium salt

Product Code:
 
TAR-T69745L
Product Group:
 
Other Biochemicals
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T69745L-1mg1 mgEnquire
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TAR-T69745L-10mg10 mgEnquire
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TAR-T69745L-100mg100 mgEnquire
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TAR-T69745L-25mg25 mgEnquire
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TAR-T69745L-5mg5 mgEnquire
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TAR-T69745L-50mg50 mgEnquire
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This product comes from: Austria.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
GDC-2394 sodium salt is an orally active selective NLRP3 inhibitor that concurrently inhibits IL-1β with IC50 values of 0.4 uM (human) and 0.1 uM (mouse). This compound specifically inhibits NLRP3-induced caspase-1 activity without affecting NLRC4-dependent inflammasome activation.
CAS Number:
2238822-08-5
Formula:
C20H24N5NaO4S
Molwt:
453.49
Pathway:
Immunology/Inflammation|NF-κB
Purity:
0.995
SMILES:
[Na+].CN[C@@H]1COC2=C(C=NN2C1)S(=O)(=O)[N-]C(=O)NC1=C2CCCC2=CC2=C1CCC2
Target:
NOD|IL Receptor

Documents