TargetMol

RI-962

Product Code:
 
TAR-T73493
Product Group:
 
Other Biochemicals
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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This product comes from: Austria.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
RI-962 is a potent and selective inhibitor of RIPK1 that dose-dependently protects cells from necrotic apoptosis induced by TNFα, Smac mimics, and Z-VAD-FMK by inhibiting RIPK1, RIPK3, and MLKL phosphorylation with EC50=10.0 nM~17.8 nM, and improves survival in mice in two models of inflammation.
CAS Number:
2763831-53-2
Formula:
C28H28N6O2
Molwt:
480.56
Pathway:
NF-κB|Apoptosis
Purity:
0.9939
SMILES:
O=C(NC(C=1C=CC=CC1)C)C2=CN(C=3C=CC(=CC23)C=4C=CN5N=C(N=C5C4)NC(=O)C(C)C)C
Target:
RIP kinase

Documents