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Further Information
Bioactivity:
Fomivirsen (ISIS-2922 free base), a 21-mer phosphorothioate antisense oligonucleotide, serves as an antiviral agent, particularly in CMV research, including AIDS studies. It functions by binding to and degrading the mRNAs that encode for the CMV immediate-early 2 protein, effectively inhibiting viral proliferation [1] [2].