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2-Chloroadenosine-5'-O-diphosphate sodium

Product Code:
 
TAR-T83785
Product Group:
 
Other Biochemicals
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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This product comes from: Austria.
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Further Information

Bioactivity:
2-Chloroadenosine-5'-O-diphosphate, a purine nucleotide adenosine 5'diphosphate (ADP) derivative, demonstrates multiple biological activities. It promotes aggregation and inhibits cyclic AMP (cAMP) production, triggered by prostaglandin E2 (PGE2), in a concentration-dependent manner within isolated human platelet-rich plasma. Additionally, this compound facilitates the relaxation of precontracted isolated guinea pig taenia coli strips (pD2 = 6.74) and reduces arterial blood pressure in rats. Moreover, 2-Chloroadenosine-5'-O-diphosphate significantly inhibits the ATPase activity of mortalin, a member of the heat shock protein 70 (Hsp70) family, with an apparent Ki of 45.05 uM for the human enzyme.
CAS Number:
82927-78-4
Formula:
C10H11ClN5O10P2.3Na
Molwt:
527.59
Pathway:
|Neuroscience|Cytoskeletal Signaling|Metabolism
SMILES:
O[C@@H]1[C@H](O)[C@@H](COP([O-])(OP([O-])([O-])=O)=O)O[C@H]1N2C=NC3=C(N)N=C(Cl)N=C32.[Na+].[Na+].[Na+]
Target:
|AChR|HSP