TargetMol

SR12343

Product Code:
 
TAR-T9055
Product Group:
 
Other Biochemicals
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
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TAR-T9055-1mg1 mgEnquire
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TAR-T9055-1mL1 mL * 10 mM (in DMSO)Enquire
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TAR-T9055-10mg10 mgEnquire
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TAR-T9055-100mg100 mgEnquire
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TAR-T9055-200mg200 mgEnquire
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TAR-T9055-25mg25 mgEnquire
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TAR-T9055-5mg5 mgEnquire
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TAR-T9055-50mg50 mgEnquire
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This product comes from: Austria.
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Further Information

Bioactivity:
SR12343 is a small molecule inhibitor of the IKK/NF-κB signaling pathway that functions as a NEMO-binding domain (NBD) mimetic. SR12343 inhibits NF-κB activation with an IC50 of 37.02 uM by specifically blocking the critical IKKβ-NEMO interaction, reduces pulmonary inflammation in models, and is suitable for research into inflammatory and degenerative diseases.
CAS Number:
2055101-86-3
Formula:
C15H15BrClN3O
Molwt:
368.66
Pathway:
NF-κB
Purity:
0.9991
SMILES:
O=C(NCCC=1C=CC=C(Br)C1)CNC2=NC=C(Cl)C=C2
Target:
NF-κB|IκB/IKK

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