TargetMol

Melicopine

Product Code:
 
TAR-TN8420
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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This product comes from: Austria.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Melicopine is an alkaloid found in Z. simulans, known for its antimalarial and anticancer properties. It inhibits P. falciparum strains, including chloroquine-sensitive 3D7 (IC50 of 29.7 ug/mL) and chloroquine-resistant Dd2 (IC50 of 33.7 ug/mL). Additionally, Melicopine exhibits cytotoxicity against prostate cancer cells PC-3M (IC50 of 47.9 ug/mL) and LNCaP (IC50 of 37.8 ug/mL), but it is inactive in non-cancerous HEK293 cells (IC50 greater than 100 ug/mL). Melicopine holds potential for research in anticancer and anti-infective applications.
CAS Number:
568-01-4
Formula:
C17H15NO5
Molwt:
313.31
Pathway:
Microbiology/Virology
SMILES:
O=C1C=2C=CC=CC2N(C3=C4OCOC4=C(OC)C(OC)=C13)C
Target:
Parasite

Documents