TargetMol

Ardeemin

Product Code:
 
TAR-TN9034
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
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TAR-TN9034-10mg10 mgEnquire
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TAR-TN9034-50mg50 mgEnquire
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This product comes from: Austria.
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Further Information

Bioactivity:
Ardeemin ((-)-Ardeemin) binds to P-glycoprotein, inhibiting the efflux of anticancer drugs from cells. In breast cancer xenograft models, Ardeemin can reverse the multidrug resistance phenotype of tumor cells and enhance their sensitivity to anticancer drugs.
CAS Number:
148441-25-2
Formula:
C26H26N4O2
Molwt:
426.51
Pathway:
Membrane transporter/Ion channel|Neuroscience
SMILES:
[C@@](C=C)(C)(C)[C@]12[C@](N3[C@@](C1)(C=4N([C@H](C)C3=O)C(=O)C=5C(N4)=CC=CC5)[H])(NC=6C2=CC=CC6)[H]
Target:
P-gp

Documents