TargetMol

Glucopiericidin A

Product Code:
 
TAR-TN9037
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
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TAR-TN9037-10mg10 mgEnquire
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TAR-TN9037-50mg50 mgEnquire
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This product comes from: Austria.
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Further Information

Bioactivity:
Glucopiericidin A is a natural piperidine-based compound found in marine-derived Streptomyces strains. It serves as a chemical probe for glucose transporter proteins (GLUT) and can inhibit glycolysis. When combined with Piericidin A (PA), it synergistically inhibits ATP-dependent filopodia formation, yet has no effect alone. Glucopiericidin A induces apoptosis by increasing PRDX1, thereby reducing reactive oxygen species (ROS) levels, and also demonstrates potent antitumor activity in ACHN mouse xenografts.
CAS Number:
108073-65-0
Formula:
C31H47NO9
Molwt:
577.706
Pathway:
Antibody-drug Conjugate/ADC Related|Metabolism|Apoptosis
SMILES:
O([C@H]([C@@H](/C=C(/C=C/C/C(=C/CC=1N=C(OC)C(OC)=C(O)C1C)/C)\C)C)/C(=C/C)/C)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O
Target:
transporter|Apoptosis|ADC Cytotoxin

Documents