TargetMol

Asterriquinone

Product Code:
 
TAR-TN9103
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TN9103-10mg10 mgEnquire
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TAR-TN9103-50mg50 mgEnquire
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This product comes from: Austria.
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Further Information

Bioactivity:
Asterriquinone (ARQ) is an analog of Asterriquinone and a Grb-2 binding inhibitor. It hinders the interaction between Grb-2 and tyrosine-phosphorylated EGFR, with an IC50 of 8.37 uM. Additionally, Asterriquinone serves as an HIV1 reverse transcriptase inhibitor, with a Ki of 2.3 uM, and it also inhibits the binding activities of Grb-7 and PLC-γ.
CAS Number:
60696-52-8
Formula:
C32H30N2O4
Molwt:
506.592
Pathway:
Proteases/Proteasome|Tyrosine Kinase/Adaptors|Angiogenesis|Microbiology/Virology|JAK/STAT signaling
SMILES:
O=C1C(O)=C(C(=O)C(O)=C1C2=CN(C=3C=CC=CC23)C(C=C)(C)C)C4=CN(C=5C=CC=CC45)C(C=C)(C)C
Target:
HIV Protease|Reverse Transcriptase|EGFR

Documents