TargetMol

Pellotine

Product Code:
 
TAR-TN9164
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TN9164-10mg10 mgEnquire
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TAR-TN9164-50mg50 mgEnquire
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Further Information

Bioactivity:
Pellotine is an alkaloid isolated from Lophophora. It acts as an inverse agonist of the 5-HT7 receptor (5-HT7 receptor), with an EC50 of 291 nM. Pellotine shows strong affinity for the 5-HT1DR and 5-HT6R, with Ki values of 117 nM and 170 nM, respectively. Additionally, Pellotine reduces intracellular cAMP levels, thereby decreasing neuronal excitability and neurotransmitter release.
CAS Number:
19622-05-0
Formula:
C13H19NO3
Molwt:
237.295
Pathway:
Neuroscience|GPCR/G Protein
SMILES:
OC=1C(OC)=C(OC)C=C2C1C(N(C)CC2)C
Target:
5-HT Receptor

Documents