TargetMol

Tkip

Product Code:
 
TAR-TP2958
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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This product comes from: Austria.
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Further Information

Bioactivity:
Tkip is a specific inhibitor of JAK2. It binds to the autophosphorylation site of JAK2, thereby inhibiting JAK2 autophosphorylation and the phosphorylation of the IFN-γ receptor subunit IFNGR-1. Tkip can suppress the antiviral activity of IFN-γ and the expression of MHC class I molecules. Tkip is applicable in studies related to the IFN-γ signaling pathway.
CAS Number:
716361-65-8
Formula:
C93H118N16O14
Molwt:
1684.03
Pathway:
Stem Cells|Immunology/Inflammation|Chromatin/Epigenetic|Angiogenesis|JAK/STAT signaling|Tyrosine Kinase/Adaptors
SMILES:
C([C@@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CC=C(O)C=C4)C(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CC6=CC=CC=C6)C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)=O)=O)=O)=O)[C@H](CC)C)=O)C(C)C)=O)=O)=O)[C@H](C)C)=O)CC(C)C)=O)N)C=7C=8C(NC7)=CC=CC8
Target:
JAK|MHC

Documents