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Further Information
Bioactivity:
VH4127 is a cyclic peptide designed to target low-density lipoprotein receptors (LDLR) with a KD of 18 nM for hLDLR. Incorporating non-natural amino acid residues, VH4127 binds specifically to epidermal growth factor (EGF) LDLR homologous domains in both rodents and humans.
