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Further Information
Bioactivity:
LAG-3cyclic peptide inhibitor C25 is an inhibitor of LAG-3. It demonstrates a high affinity for human LAG-3 protein with a dissociation constant (Kd) of 0.66 uM. This compound can block the interaction between LAG-3 and HLA-DR (MHC-II), thereby activating CD8+ T cells. LAG-3cyclic peptide inhibitor C25 is applicable in tumor research.