TargetMol

KRL74

Product Code:
 
TAR-TP2983
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TP2983-10mg10 mgEnquire
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TAR-TP2983-50mg50 mgEnquire
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This product comes from: Austria.
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Further Information

Bioactivity:
KRL74 is a cyclic peptide inhibitor that interferes with the interaction between the p6 domain of the HIV Gag protein and the UEV domain of the human TSG101 protein (p6/UEV), with an IC50 of 5.44 uM and a Kd of 11.9 uM. It also inhibits the budding of HIV from host cells, exhibiting an IC50 of 2 uM in virus-like particle (VLP) budding assays.
CAS Number:
2423969-43-9
Formula:
C50H61ClN10O9
Molwt:
981.53
Pathway:
|Proteases/Proteasome|Microbiology/Virology
SMILES:
C(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@H](CC4=CC=C(Cl)C=C4)NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@H](CC=5C=6C(NC5)=CC=CC6)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C)NC3=O)[H]
Target:
|HIV Protease

Documents