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Further Information
Bioactivity:
BT1769 is a bicyclic toxin conjugate targeting MT1-MMP (Matrilysin 1 type-MMP) with a KD of 3.35 nM. It is utilized for osteosarcoma research. BT1769 comprises an innovative bicyclic targeting peptide that selectively binds to MT1-MMP, a cytotoxin MMAE, and a dipeptide linker that can be enzymatically cleaved.
