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Further Information
Bioactivity:
ER-DRI is a potent peptide inhibitor that targets EV-A71. It directly binds to 3A and specifically neutralizes the activity of RNAi virus suppressor factors, thereby unlocking the antiviral RNAi response inhibited by 3A. ER-DRI also effectively inhibits another RNAi-dependent enterovirus, Coxsackievirus A16.