TargetMol

PIC1 PA

Product Code:
 
TAR-TP3013
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TP3013-10mg10 mgEnquire
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TAR-TP3013-50mg50 mgEnquire
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This product comes from: Austria.
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Further Information

Bioactivity:
PIC1 PA, a peptide consisting of 15 amino acids, serves as an effective analog of PIC1 that inhibits complement activation mediated by the classical pathway. Functionally, PIC1 PA interferes with the interaction between the C1s-C1r-C1r-C1s/MASPs and the collagen-like region (CLR) of C1q/MBL. It specifically binds to the CLR of C1q, with an average equilibrium dissociation constant (KD) of 33.3 nM when binding purified C1q.
CAS Number:
1356469-36-7
Formula:
C71H123N19O21S2
Molwt:
1642.98
Pathway:
Immunology/Inflammation
SMILES:
C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)C)=O)CC(C)C)=O)[C@H](CC)C)=O)CC(C)C)=O)CCC(O)=O)(=O)N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)C)=O)CCCNC(=N)N)=O)CCC(O)=O)=O)CCC(N)=O)=O)CS)=O)CS)=O)[C@H](CC)C)=O)CCC1
Target:
Complement System

Documents