TargetMol

CNI103

Product Code:
 
TAR-TP3040
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
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This product comes from: Austria.
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Further Information

Bioactivity:
CNI103 is a potent and metabolically stable inhibitor of the cell-permeable peptide, calcineurin. It selectively inhibits the interaction between calcineurin and NFATc3 (KD=16 nM), thereby preventing the activation of NFATc3 both in vitro and in vivo. CNI103 is applicable for research in acute respiratory distress syndrome (ARDS) and other inflammatory diseases.
CAS Number:
2366279-86-7
Formula:
C116H180Cl2N36O26
Molwt:
2565.8
Pathway:
Metabolism
SMILES:
C(C1=CC2=C(C=C1)C=CC=C2)[C@@H]3NC(=O)[C@@H](CC4=CC=CC=C4)NC(=O)[C@H](CCC(NCCCC[C@H](NC(COCCOCCNC([C@@H](NC([C@H](NC([C@H](CC5=CN=CN5)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)C=6C(Cl)=C(Cl)N=CC6)[C@@](C)(C)C)=O)[C@H](CC)C)=O)C(C)(C)O)=O)[C@H](CC)C)=O)[C@@H](C)O)=O)CCC(N)=O)=O)=O)CC(C)C)=O)CO)=O)=O)C(N)=O)=O)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC3=O
Target:
Phosphatase

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