TargetMol

Cyclic(YCDGFYACYMDV)

Product Code:
 
TAR-TP3053
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
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This product comes from: Austria.
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Further Information

Bioactivity:
Cyclic(YCDGFYACYMDV) is a HER2 signaling pathway inhibitor with anticancer properties. In aqueous solution, Cyclic(YCDGFYACYMDV) self-assembles into nanoparticles that target HER2 on cancer cells, converting into nanofibrils. This process disrupts HER2 dimerization and subsequent downstream signaling, leading to apoptosis (Apoptosis) of cancer cells. Its inhibitory effect on HER2-positive breast cancer has been demonstrated as effective in mouse xenograft models.
CAS Number:
535959-77-4
Formula:
C65H82N12O20S3
Molwt:
1447.61
Pathway:
Tyrosine Kinase/Adaptors|Apoptosis|Angiogenesis|JAK/STAT signaling
SMILES:
[C@H](CC1=CC=C(O)C=C1)(C(N[C@H](C(N[C@H](C(N[C@@H](C(C)C)C(O)=O)=O)CC(O)=O)=O)CCSC)=O)NC(=O)[C@H]2NC(=O)[C@H](C)NC(=O)[C@H](CC3=CC=C(O)C=C3)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC([C@H](CC5=CC=C(O)C=C5)N)=O)CSSC2
Target:
Apoptosis|EGFR

Documents