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Further Information
Bioactivity:
Entolimod (CBLB-502) is a recombinant protein that serves as an agonist for Toll-like receptor 5 (TLR5). It triggers the TLR5-NF-κB signaling cascade, leading to the mobilization of various components of both innate and adaptive immunity to the liver, subsequently inhibiting liver metastases and establishing long-term antitumor immune memory.