TargetMol

FOG-001

Product Code:
 
TAR-TP3124
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-TP3124-10mg10 mgEnquire
Quantity:
TAR-TP3124-50mg50 mgEnquire
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges to UK mainland customers, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: Austria.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Bioactivity:
FOG-001 is an efficient inhibitor of β-catenin, with an IC50 value lower than 50 nM. This compound can block the interaction between β-catenin and T-cell factor (TCF) transcription factors, thereby interfering with the related signaling pathways. FOG-001 can effectively inhibit cell proliferation and induce cell cycle arrest. In a mouse xenograft tumor model carrying COLO320DM colon cancer cells (with APC and TP53 mutations), FOG-001 exhibits significant anti-tumor activity. Therefore, FOG-001 is applicable to the research on the mechanism of colon cancer occurrence and treatment.
CAS Number:
3044032-95-0
Formula:
C102H134N18O25S2
Molwt:
2076.39
Pathway:
Stem Cells|Cytoskeletal Signaling
Target:
Wnt/beta-catenin

Documents