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Further Information
Bioactivity:
TAT-CBD3A6K acetate is a modified TAT-CBD3 peptide. It decreases T-type and R-type voltage-dependent calcium currents in dorsal root ganglion (DRG) neurons. By inhibiting CRMP-2 mediated enhancement of T-type and R-type calcium channel functions, TAT-CBD3A6K acetate demonstrates anti-nociception in a model of AIDS-induced peripheral neuropathy.
