TargetMol

MACTIDE-V

Product Code:
 
TAR-TP3253
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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CodeSizePrice
TAR-TP3253-10mg10 mgEnquire
Quantity:
TAR-TP3253-50mg50 mgEnquire
Quantity:
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This product comes from: Austria.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
MACTIDE-V is an orally active and selective peptide-drug conjugate targeting CD206. This compound delivers Verteporfin to CD206+ tumor-associated macrophages (TAM), thereby inhibiting the YAP/TAZ signaling pathway. It facilitates YAP exclusion from the nucleus, induces TAM polarization toward an anti-tumor phenotype, enhances phagocytosis and antigen presentation, and promotes T cell infiltration and NK cell activity. MACTIDE-V suppresses primary tumor growth and lung metastasis in triple-negative breast cancer (TNBC) mouse models.
Formula:
C109H156N22O27S2
Pathway:
Stem Cells|Chromatin/Epigenetic
Target:
YAP|Epigenetic Reader Domain

Documents