TargetMol

ssK36

Product Code:
 
TAR-TP3290
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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CodeSizePrice
TAR-TP3290-10mg10 mgEnquire
Quantity:
TAR-TP3290-50mg50 mgEnquire
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This product comes from: Austria.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
ssK36 is a super-substrate peptide derived from the histone methyltransferase (SET) domain protein 2 (SETD2). This peptide was specifically designed for SETD2, a unique PKMT responsible for methylating the 36th lysine residue on histone H3 (H3K36) in human cells, resulting in H3K36me3. Remarkably, ssK36 undergoes methylation by SETD2 at a rate over 100 times faster than the natural substrate H3K36. ssK36 serves as a valuable tool for investigating the catalytic mechanisms of PKMTs, particularly regarding substrate specificity and catalytic efficiency.
Formula:
C79H127N29O18
Pathway:
Chromatin/Epigenetic
Target:
Histone Methyltransferase

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