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Further Information
Bioactivity:
The compound cpm-1285m is a cell-permeable mutant peptide analog of cpm-1285 (Bcl-2 inhibitory peptide). It features a single alanine substitution for Leu-151, resulting in reduced Bcl-2 binding affinity, with an IC50 approximately 15 times lower. cpm-1285m can serve as a control for cpm-1285.