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Further Information
Bioactivity:
ShK-Dap22 TFA is a potent and specific Kv1.3 immunosuppressive polypeptide. It acts as a selective Kv1.3 channel blocker, exhibiting IC50 values of 23 pM for mKv1.3, 1.8 nM for mKv1.1, 10.5 nM for hKv1.6, 37 nM for mKv1.4, and 39 nM for rKv1.2 channels.