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Further Information
Bioactivity:
TAT-GluR6-9c is a blocker of GluR6-PSD95 interaction. It inhibits JNK activation and c-Jun phosphorylation by regulating GluR6-mediated signaling pathways, thereby reducing Fas L expression and decreasing apoptosis. TAT-GluR6-9c is applicable in the study of cerebral ischemia and neuroprotection strategies.