TargetMol

Q14

Product Code:
 
TAR-TP3624
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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CodeSizePrice
TAR-TP3624-10mg10 mgEnquire
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TAR-TP3624-50mg50 mgEnquire
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This product comes from: Austria.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Q14 is a polypeptide derived from the transmembrane (TM) domain of USP30 (ubiquitin specific peptidase30) and is capable of inhibiting the deubiquitination activity of USP30 (IC50=57.2 nM). By hindering the interaction between USP30?s transmembrane and catalytic domains, it lowers USP30 activity. The Q14 polypeptide contains an LC3 interaction region (LIR) motif, enabling it to bind with LC3, thereby accelerating autophagosome formation and promoting mitophagy. Q14 is applicable in the study of neurodegenerative diseases, mitochondrial quality control, and cellular metabolism.
Formula:
C101H168N32O23
Pathway:
Ubiquitination|DNA Damage/DNA Repair|Cell Cycle/Checkpoint|Autophagy
Target:
Mitophagy|DUB

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