TargetMol

Alloc-Val-Ala-OH

Product Code:
 
TAR-TYD-01870
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-TYD-01870-10mg10 mgEnquire
Quantity:
TAR-TYD-01870-50mg50 mgEnquire
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges to UK mainland customers, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: Austria.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Bioactivity:
Alloc-Val-Ala-OH (((Allyloxy)carbonyl)-L-valyl-L-alanine) serves as a building block in the synthesis of Tesirine, which is a clinical antibody-drug conjugate (ADC) featuring a pyrrolobenzodiazepine (PBD) dimer payload. The Val-Ala sequence is cleaved specifically by cathepsin B. The Alloc group is stable towards piperidine and TFA, yet can be easily removed under mild conditions via palladium-catalyzed allyl transfer.
CAS Number:
330970-70-2
Formula:
C12H20N2O5
Molwt:
272.298
SMILES:
[C@H](C(N[C@H](C(O)=O)C)=O)(NC(OCC=C)=O)C(C)C

Documents