TargetMol

C14-490

Product Code:
 
TAR-TYD-01884
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-TYD-01884-10mg10 mgEnquire
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TAR-TYD-01884-50mg50 mgEnquire
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This product comes from: Austria.
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Further Information

Bioactivity:
C14-490 is an ionizable cationic lipid (pKa= 5.94) utilized in the synthesis of lipid nanoparticles (LNPs). These LNPs serve as a platform for subsequent gene editing studies in hematopoietic stem cells (HSCs) in utero. C14-490 LNPs encapsulate SpCas9 mRNA and TTR sgRNA, employing an optimized B5 formulation parameter, and are further enhanced by the surface attachment of CD45 antibody F(ab?)2 fragments to create Systemically Targeted Editing Mechanism LNPs (STEM LNPs).
CAS Number:
2639634-82-3
Formula:
C86H177N5O7
Molwt:
1393.35
Pathway:
Metabolism
SMILES:
OC(CN(CCN1CCN(CC1)CC(OCC)CN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)CC(OCC)CN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)CCCCCCCCCCCC
Target:
Liposome

Documents