TargetMol

Mal-amide-PEG8-Val-Cit-PAB-PNP

Product Code:
 
TAR-TYD-01921
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TYD-01921-50mg50 mgEnquire
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Further Information

Bioactivity:
Mal-amide-PEG8-Val-Cit-PAB-PNP is a cleavable ADC linker comprising a maleimide group, a PEG spacer, a Val-Cit dipeptide, PAB, and a PNP carbonate. The maleimide serves as a thiol-specific covalent connector for labeling cysteine residues in proteins, whereas the PNP group acts as a highly reactive leaving group. The Val-Cit linker is cleaved by cytoplasmic peptidases.
CAS Number:
1964490-09-2
Formula:
C51H74N8O20
Molwt:
1119.18
Pathway:
Antibody-drug Conjugate/ADC Related
SMILES:
N(C([C@@H](NC([C@@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(=O)C=CC1=O)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C2=CC=C(COC(OC3=CC=C(N(=O)=O)C=C3)=O)C=C2
Target:
ADC Linker

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