TargetMol

Mal-amide-PEG8-Val-Cit-PAB-OH

Product Code:
 
TAR-TYD-01936
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TYD-01936-10mg10 mgEnquire
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TAR-TYD-01936-50mg50 mgEnquire
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This product comes from: Austria.
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Further Information

Bioactivity:
Mal-amide-PEG8-Val-Cit-PAB-OH is a cleavable ADC linker, featuring a maleimide group, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB moiety. The maleimide group allows covalent bonding to free thiols on cysteine residues of proteins. The Val-Cit dipeptide is cleaved intracellularly by cathepsins to facilitate payload delivery via the PAB structure.
CAS Number:
2387738-43-2
Formula:
C44H71N7O16
Molwt:
954.072
Pathway:
Antibody-drug Conjugate/ADC Related
SMILES:
N(C([C@@H](NC([C@@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(=O)C=CC1=O)=O)=O)[C@@H](C)C)=O)CCCNC(N)=O)=O)C2=CC=C(CO)C=C2
Target:
ADC Linker

Documents