TargetMol

Boc-PEG2-Val-Cit-PAB-OH

Product Code:
 
TAR-TYD-01991
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-TYD-01991-10mg10 mgEnquire
Quantity:
TAR-TYD-01991-50mg50 mgEnquire
Quantity:
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This product comes from: Austria.
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Further Information

Bioactivity:
Boc-PEG2-Val-Cit-PAB-OH is an enzymatically cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzyl alcohol on PAB can be utilized for attachment to reactive groups (such as PNP) to connect with a drug payload. The Boc protecting group can be removed with acid, revealing a primary amine that serves for coupling reactions to form an amide. The Val-Cit-PAB segment is cleaved by cellular proteases, facilitating the effective release of the payload inside the cell.
CAS Number:
2055024-55-8
Formula:
C30H50N6O9
Molwt:
638.753
Pathway:
Antibody-drug Conjugate/ADC Related
SMILES:
[C@H](C(NC1=CC=C(CO)C=C1)=O)(NC([C@@H](NC(CCOCCOCCNC(OC(C)(C)C)=O)=O)[C@H](C)C)=O)CCCNC(N)=O
Target:
ADC Linker

Documents