TargetMol

MC-val-ala-nhs ester

Product Code:
 
TAR-TYD-02069
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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This product comes from: Austria.
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Further Information

Bioactivity:
MC-Val-Ala-NHS ester is a cleavable ADC linker featuring maleimide and NHS ester groups. The Val-Ala linker is susceptible to cleavage by cathepsin B. The maleimide group can react with thiol groups, as can the MC component. The NHS ester reacts specifically and efficiently with amines (such as lysine residue side chains or aminosilane-coated surfaces) under neutral or mildly alkaline conditions, forming covalent bonds. Reagent grade, intended for research use only.
CAS Number:
1895916-22-9
Formula:
C22H30N4O8
Molwt:
478.496
Pathway:
Antibody-drug Conjugate/ADC Related
SMILES:
O(C([C@@H](NC([C@@H](NC(CCCCCN1C(=O)C=CC1=O)=O)[C@@H](C)C)=O)C)=O)N2C(=O)CCC2=O
Target:
ADC Linker

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