TargetMol

Alloc-Val-Ala-pAB

Product Code:
 
TAR-TYD-02095
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-TYD-02095-10mg10 mgEnquire
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TAR-TYD-02095-50mg50 mgEnquire
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This product comes from: Austria.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Alloc-Val-Ala-PAB is a cleavable peptide linker employed in the synthesis of antibody-drug conjugates (ADC). The Val-Ala sequence is specifically cleaved by cathepsin B. The Alloc group remains stable when treated with piperidine and TFA, yet it can be easily removed under mild conditions via palladium-catalyzed allyl transfer.
CAS Number:
1343407-91-9
Formula:
C19H27N3O5
Molwt:
377.435
Pathway:
Antibody-drug Conjugate/ADC Related
SMILES:
N(C([C@@H](NC([C@@H](NC(OCC=C)=O)[C@@H](C)C)=O)C)=O)C1=CC=C(CO)C=C1
Target:
ADC Linker

Documents