TargetMol

(R)-KMH-233

Product Code:
 
TAR-TYD-02664
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-TYD-02664-10mg10 mgEnquire
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TAR-TYD-02664-50mg50 mgEnquire
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This product comes from: Austria.
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Further Information

Bioactivity:
(R)-KMH-233 is an isomer of KMH-233, which can serve as a reference compound in experiments. KMH-233 functions as a potent, reversible, and selective inhibitor of L-type amino acid transporter 1 (LAT1), effectively hindering the uptake of LAT1 substrate, l-leucine (IC50=18 uM), and also inhibiting cell growth. Even at a low concentration of 25 uM, KMH-233 significantly enhances the efficacy of Bestatin and cisplatin.
CAS Number:
2994330-89-9
Formula:
C32H25N7O5
Molwt:
587.58
Pathway:
Membrane transporter/Ion channel
SMILES:
N(C(=O)C1=CC(C[C@H](C(O)=O)N)=CC=C1)C=2N3C(C(C#N)=C(C2C#N)C4=CC=C(OCC(NC)=O)C=C4)=NC=5C3=CC=CC5
Target:
ASCT

Documents