GLP-1R (human) (rec.) (His) (Biotin)
Product Code:
AG-40B-0279B
AG-40B-0279B
Host Type:
HEK 293 cells
HEK 293 cells
Regulatory Status:
RUO
RUO
Target Species:
- Bovine (Cattle)
- Human
- Mouse
- Rat
Shipping:
Blue Ice
Blue Ice
Storage:
Short term: 4°C. Long term: -20°C.
Short term: 4°C. Long term: -20°C.
No additional charges, what you see is what you pay! *
| Code | Size | Price |
|---|
| AG-40B-0279B-C050 | 50 ug | £301.00 |
Quantity:
Prices exclude any Taxes / VAT
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This product comes from: Switzerland.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
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Further Information
Concentration:
After reconstitution: 1mg/ml
Description:
Glucagon-like peptide 1 (GLP-1) is a 30-amino acid Incretin peptide hormone produced in the intestine by differential processing of proglucagon. Incretin hormones are gut peptides that are secreted after nutrient intake and stimulate insulin secretion together with hyperglycemia. GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) are the known incretin hormones from the upper (GIP, K cells) and lower (GLP-1, L cells) gut. GLP-1 receptors are abundant in the hypothalamus which contains projections to the hunger centers. GLP-1 decreases calorie intake, boosts feelings of satiety and encourages weight loss. GLP-1 and GIP hormones are used as drugs for weight loss in obese patients and also to lower blood sugar levels. GLP-1R (human) (rec.) (His) (Biotin) can be used with a streptavidin coated plate to screen new GLP-1 analogs.
EClass:
32160000
Endotoxin:
<0.01 EU/ug protein (LAL test).
Form:
solid
Formulation:
Lyophilized. Contains PBS.
Handling Advice:
After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0. 1% BSA should be used for further dilutions.
Labels - Conjugates:
Biotin
Long Description:
Recombinant Protein. Extracellular domain of human GLP-1R (aa 24-139) is fused at the C-terminus to the His-Tag and is biotinylated. Produced in HEK 293 cells. Produced using animal component-free medium. Glucagon-like peptide 1 (GLP-1) is a 30-amino acid Incretin peptide hormone produced in the intestine by differential processing of proglucagon. Incretin hormones are gut peptides that are secreted after nutrient intake and stimulate insulin secretion together with hyperglycemia. GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) are the known incretin hormones from the upper (GIP, K cells) and lower (GLP-1, L cells) gut. GLP-1 receptors are abundant in the hypothalamus which contains projections to the hunger centers. GLP-1 decreases calorie intake, boosts feelings of satiety and encourages weight loss. GLP-1 and GIP hormones are used as drugs for weight loss in obese patients and also to lower blood sugar levels. GLP-1R (human) (rec.) (His) (Biotin) can be used with a streptavidin coated plate to screen new GLP-1 analogs.
Molecular Weight:
~35-40kDa (SDS-PAGE)
NCBI, Uniprot Number:
P43220
Package Type:
Plastic Vial
Purity:
>95% (SDS-PAGE)
Sequence:
Extracellular domain of human GLP-1R (aa 24-139) is fused at the C-terminus to the His-Tag and is biotinylated.
TAGs:
His
Transportation:
Non-hazardous
UNSPSC Category:
Other Proteins
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.