8-Anilino-1-naphthalenesulfonic acid
Product Code:
CDX-A0112
CDX-A0112
Regulatory Status:
RUO
RUO
Shipping:
Ambient
Ambient
Storage:
Short term: +20°C. Long term: +20°C.
Short term: +20°C. Long term: +20°C.
No additional charges, what you see is what you pay! *
| Code | Size | Price |
|---|
| CDX-A0112-G025 | 25 g | £116.00 |
Quantity:
| CDX-A0112-G100 | 100 g | £330.00 |
Quantity:
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This product comes from: Switzerland.
Typical lead time: 7-10 working days.
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Typical lead time: 7-10 working days.
Contact us for more accurate information.
- Further Information
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Further Information
Appearance:
Gray to dark green to black powder.
CAS:
82-76-8
EClass:
32160000
Form:
solid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C16H13NO3S/c18-21(19,20)15-11-5-7-12-6-4-10-14(16(12)15)17-13-8-2-1-3-9-13/h1-11,17H,(H,18,19,20)
InChiKey:
FWEOQOXTVHGIFQ-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 82-76-8. Formula: C16H13NO3S. MW: 299.34. 8-Anilino-1-naphthalenesulfonic acid (ANS) is a widely used environment-sensitive fluorescent probe for studying protein structure, conformational changes, and hydrophobic surface exposure. ANS exhibits weak fluorescence in aqueous solutions but shows a strong increase in fluorescence intensity and a blue shift in emission upon binding to hydrophobic regions of proteins, membranes, or macromolecular complexes. This property makes ANS an essential tool for protein folding/unfolding studies, ligand-binding assays, and investigations of protein-protein interactions. It is commonly applied in biochemical and biophysical research to monitor changes in protein conformation under varying conditions such as pH, temperature, or denaturant concentration. Spectral data: lambdaex 371 nm, lambdaem 480 nm in methanol.
MDL:
MFCD00003998
Molecular Formula:
C16H13NO3S
Molecular Weight:
299.34
Package Type:
Vial
Product Description:
8-Anilino-1-naphthalenesulfonic acid (ANS) is a widely used environment-sensitive fluorescent probe for studying protein structure, conformational changes, and hydrophobic surface exposure. ANS exhibits weak fluorescence in aqueous solutions but shows a strong increase in fluorescence intensity and a blue shift in emission upon binding to hydrophobic regions of proteins, membranes, or macromolecular complexes. This property makes ANS an essential tool for protein folding/unfolding studies, ligand-binding assays, and investigations of protein-protein interactions. It is commonly applied in biochemical and biophysical research to monitor changes in protein conformation under varying conditions such as pH, temperature, or denaturant concentration. Spectral data: lambdaex 371 nm, lambdaem 480 nm in methanol.
Purity:
>97% (HPLC)
SMILES:
O=S(=O)(O)C1=CC=CC2=CC=CC(NC=3C=CC=CC3)=C21
Solubility Chemicals:
Soluble in DMSO (20mg/ml), DMF (50 mg/ml) or methanol (20mg/ml). Slightly soluble in water (<1mg/ml).
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at RT.
Documents
References
[1] N. Gains & A.P. Dawson AP; Biochem. J. 148, 157 (1975) | [2] V. Cody & J. Hazel; BBRC 68, 425 (1976) | [3] X.C. Yu & H.W. Strobel; Mol. Cell Biochem. 162, 89 (1996) | [4] J. Ishida, et al.; Biol. Pharm. Bull. 19, 1391 (1996) | [5] J. Malecki & Z. Wasylewski; J. Protein Chem. 17, 745 (1998) | [6] M. Andujar-Sanchez, et al.; J. Mol. Recognit. 24, 548 (2011) | [7] H.K. Vivek, et al.; Anal. Biochem. 461, 27 (2014) | [8] C. Ota & K. Takano; Chemphyschem. 20, 1456 (2019) | [9] E.B. Faber, et al.; ACS Chem. Biol. 15, 1759 (2020)