Elabscience

UM-Chor1 Cell Line

Product Code:
CL-0951
Product Group:
Cell Lines
Supplier:
Elabscience
Host Type:
Human
Regulatory Status:
RUO
Shipping:
Dry Ice
Storage:
For long-term cryopreservation, cryovials should be stored in liquid nitrogen at -150°C to -196°C. Storage at -80°C is restricted to short-term interim use only.
 

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This product comes from: China.
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Further Information

Age Gender:
64Y, Male
Background:
UM-Chor1 is a mesenchymal cell line isolated in 2012 from the clivus of a 64-day-old White male patient with clival chordoma prior to treatment. UM-Chor1 represents the first validated human clival chordoma cell line. It exhibits chordoma-like phenotypes and bears the characteristic molecular, genetic, and morphological hallmarks of chordoma. The cell line was established from a suprasellar lesion composed of solid, cystic, and hemorrhagic components; the primary tumor extended along the clivus into the ethmoid sinuses. Flow cytometry was used to purify primary cultures, and the NCAM-positive cell population was expanded to generate the UM-Chor1 chordoma cell line. Cells express transcription factor T (TBXT, brachyury), the most specific diagnostic marker for chordoma.
Biosafety Level:
BSL-1
Cryopreservation:
General Freezing Medium [PB180436]
Culture medium:
71.2% IMDM [PM150510]+17.8% RPMI-1640 [PM150110]+10% Nutrient+1% Supplement
Dissociation Duration:
3-4 min
Growth properties:
Adherent
Incubation Atmosphere:
Air, 95%; CO2, 5%,37°C
Medium Renewal:
every 2 to 3 days
Morphology:
Epithelial-like
Subcultivation Ratio:
1~2
Tissue:
Bone; Clivus

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